Welcome to the Hjelt Foundations

"The three Hjelt Foundations, Spina Bifida, Diabetes and Art were created because of very important events that have considerably influenced my life."

 Bo Hjelt

News

By The Diabetes Foundation October 20, 2024
The Diabetes Foundation: The application period for next year’s research grants is 20 October to 15 December. Research grants are awarded to applicants at the Medical Faculties of Lund University, Sweden and Geneva University, Switzerland. Read more and apply at "Research Grants".
By The Art Foundation October 18, 2024
Two expert presentations at Helsinki Book Fair on Aino and Alvar Aalto's Italian connections
By The Sibelius Museum, Åbo, Finland May 30, 2024
The exhibition "More than just oldsters" presents the art that has been donated to the Åbo Akademi University Foundation, as well as its donators.
This spring we have the pleasure to invite two circus educators Lena Kruit and Rieke Hambach
By The Art Foundation May 3, 2024
We have the pleasure to invite two circus educators Lena Kruit and Rieke Hambach from MeerManege in Kiel, Germany to give a Hjelt talk, demonstrating the importance of play for creativity, the benefit of play and how it is linked to Education for Sustainable Development.
September 5, 2023
Jiangming Sun, Emma Ahlqvist and Sabrina Ruhrmann have each been awarded a project grant of 47,500 euro by the Hjelt Diabetes Foundation.
By The Art Foundation May 17, 2023
Allan and Bo Hjelt Art Foundation had the great honour to welcome Mr. Leonardo Ferragamo, Chairman of Nautor Swan, to give an inspirational design talk on Finnish-Italian collaboration in Helsinki in March.
By The Diabetes Foundation October 19, 2022
The Diabetes Foundation: The application period for next year’s research grants is 19 October to 15 December. Research grants are awarded to applicants at the Medical Faculties of Lund University, Sweden and Geneva University, Switzerland. Read more/apply
By The Diabetes Foundation September 8, 2022
Today, three of our grant holders in the Diabetes foundation for 2022 are presented in an article on the Lund University Diabetes Center website. Read more at the LUDC web site .
By The Art Foundation March 31, 2022
Sir John Stuttard: "Pre-War Rolls-Royce Motor Cars with a Finnish connection" Time: Wed, April 27th 2022 at 5 pm Venue: Handelsgilletin juhlasali, Kasarminkatu 40, 2. krs., Helsinki Lecture in English. Due to limited seats available, pre-registration is required to art@hjeltfoundations.org. Welcome!
By The Diabetes Foundation March 4, 2022
We are pleased to announce that four scientists have been awarded the Hjelt Research Grant for 2022: Luis Rodrigo Cataldo Bascunan, Anja Schmidt-Christensen and Sebastian Kalamajski, Lund University Diabetes Centre, and Monika Gjorgijeva Ducros, University of Geneva Faculty of Medicine Diabetes Centre.
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Spina Bifida Foundation

Having lost a child due to Spina Bifida, a most traumatic experience that no family should have to go through, the Bo Hjelt Foundation for Spina Bifida in memory of Madeleine Hjelt was set up to aid research into its’ prevention.
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Diabetes Foundation

The Bo and Kerstin Hjelt Foundation for research into Diabetes II was set up because, being a diabetic himself, he wanted to contribute to research in this field as it is increasing rapidly worldwide.
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Art Foundation

The Allan and Bo Hjelt Art Foundation was created in honour of Bo Hjelt's parents. He wanted to return to Finland some pieces of art that his Finnish-born father had collected; and to create the Falsterbonaset Open Air Museum in memory of his mother’s happy times in Falsterbo (five bronze statues by the Swedish sculptor Gudmar Olovson).
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Diabetes Foundation: Our Recent Research Projects

Etienne Delangre
January 16, 2025
Etienne Delangre, Hjelt Grant Holder 2024, University of Geneva. Therapeutic potential of S100A10 Inhibition in Hepatic Insulin Resistance, MASLD and Type 2 Diabetes
December 16, 2024
Rashmi B. Prasad , Hjelt Grant Holder 2024, Lund University. Towards Personalized Medicine: Unraveling Biomarkers in Gestational Diabetes for Predicting Diabetes Subtypes and Prevention
March 7, 2024
Sebastian Kalamajski, Hjelt Grant Holder 2024, Lund University. Leveraging discordancy between obesity and type 2 diabetes to target insulin resistance
By Hjelt Grant Holder 2023, Sabrina Ruhrmann March 21, 2023
Sabrina Ruhrmann, Hjelt Grant Holder 2023, Lund University. Epigenetic Editing - a way to a personalized treatment approach in type 2diabetes (T2D) The number of people affected by diabetes is rapidly increasing worldwide. Type 2 diabetes (T2D) largely contributes to this increase and individuals with T2D usually face high blood sugar levels. To balance our blood sugar level the hormone Insulin is necessary and Insulin target tissues like muscles need to be able to take up glucose in response to Insulin. Overweight and no physical exercise can lead to insulin resistance (where the uptake of glucose is not any longer possible e.g. in our muscles) and almost all individuals with T2D show Insulin resistance. Our DNA only explains a small proportion of how T2D is passed on from parents to their children (also described as the so called “missing heritability”). Given the crucial role of diet and physical exercise in the development of T2D, mechanisms mediating the interaction of those factors with our genes should be of particular importance when trying to explain how T2D develops. Epigenetic mechanisms fulfil this criterion. Epigenetics is the study of how e.g. the environment and/or our behavior can affect the expression of our genes without changing our DNA. The fact that epigenetic changes do not change our DNA unlike genetic changes gives us the opportunity to “correct“ them. We are here trying to discover epigenetic changes that cause T2D. We will create small molecules called guideRNAs (gRNAs) that will help us to search for those epigenetic changes using the so called inactivated gene scissor system, CRISPR-dCas9. We will further try to also 'correct' these epigenetic changes to explore if epigenetic mechanisms may be targeted for a more patient specific treatment of T2D in the future.
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